COVID-19 Clinical Resources and Pertinent Research
A regularly updated list of the most useful COVID-19 clinical resources, the most significant research publications, and reliable news. To contribute, click the plus button on the left. Short URL:

COVID-19 Clinical Resources

Quick Reference Cards

  1. COVID-19 Treatment and Management
    1. Critical Care Treatment Algorithm
    2. Respiratory Failure
    3. ICU Management
    4. Drugs & Treatment (WHO Rx & NIH Rx Diagrams)
    5. Inpatient Management
    6. Outpatient Management
    7. Treatment Algorithm for Hospitalized Adults
    8. Treatment Algorithm for Non-Hospitalized Adults
      (Note on 11/20 the WHO Recommended Against the Use of Remdesivir in the Treatment of COVID-19)
  2. COVID-19 ICU Quick Reference Protocols
  3. Critical Care Meds and Parameters Quick Reference
  4. Nasal Oxygen Delivery One Pager
  5. COVID-19 Intubation Checklists
    1. Basics of Mechanical Ventilation
    2. Overview of Ventilator Modes
    3. Ventilator Management Algorithm
    4. Ventilator Troubleshooting
    5. Volume Assist/Control Ventilation
    6. Weaning from the Ventilator
    7. Respiratory Care Pocket Reference
  6. ARDS Overview
    1. ARDSnet Mechanical Ventilation Protocol
    2. Tidal Volume Quick Reference
    3. APRV Overview
    4. SSC Recommendations
  7. Critical Care and ICU Management
    1. Vasopressors Quick Reference
    2. Pulmonary POCUS Pocket Guide
    3. Algorithm for Use of Inhaled Pulmonary Vasodilators in Refractory Hypoxemia
    4. Acid Base Disorders Quick Reference
    5. Shock Quick Reference
  8. COVID-19 Resuscitation
    1. ACLS COVID-19 Cardiac Arrest Algorithm
    2. BLS COVID-19 Cardiac Arrest Algorithm
  9. ICU Checklist for Non-Critical Care Providers

Clinical Guidelines and Protocols

  1. NIH COVID-19 Treatment Guidelines
  2. WHO Guideline on Drugs for COVID-19
  3. IDSA COVID-19 Treatment and Management Guidelines
  4. Brigham & Women’s COVID-19 Clinical Guidelines
  5. Open Critical Care COVID Guidelines Dashboard
  6. EM:RAP – COVID-19
  7. EMCrit – COVID-19
    1. COVID-19 Intubation Packs and Preoxygenation for Intubation
    2. COVID-19 Airway Management Tips
    3. COVID-19 Guide to APRV
  8. UpToDate – COVID-19
    1. ARDS: Oxygenation and Supportive Care
    2. ARDS: Ventilator Management Strategies
    3. ARDS: Prone Ventilation
    4. ECMO
  9. DynaMed – COVID-19
  10. ACP – COVID-19 Clinical Guidance
  11. Australian Guidelines for the Clinical Care of COVID-19
  12. ICM – COVID-19 Clinical Guidance
  13. SCCM – Critical Care for the Non-ICU Clinician
  14. Institution Specific Protocols List

Mechanical Ventilation Info

  1. Open Critical Care – Oxygen Supply & Delivery FAQ
  2. PulmCrit – Guide to Splitting Ventilators
    1. How to Use One Ventilator to Save Multiple Lives
    2. LITFL: Shared Ventilation: How To Do It If You Have To
  3. COVID-19 Ventilator Simulator
  4. COVID-19 Ventilator Course
    1. Mechanical Ventilation Explained Clearly – Ventilator Settings & Modes
    2. Pathophysiology and Ventilator Management of ARDS in COVID-19
    3. How To Modify a Bi-Pap Machine into a Ventilator
    4. How To Modify a Resmed VPAP Machine into a Ventilator
  5. Respiratory Care and Ventilator Setup Training
  6. VentICalc: Respiratory Mechanics Calculator

Personal Protective Equipment (PPE)

  1. Personal Protective Equipment for COVID-19
    1. 3M Health Care Surgical Mask and Respirator Types
    2. How to Identify a NIOSH-Approved N95 (More Info)
    3. List of NIOSH Approved Respirator Makes and Models
  2. CDC: Donning and Doffing Sequence for PPE
  3. Performing a Seal Check When Donning an N95
  4. CDC: Decontamination and Reuse of Filtering Facepiece Respirators (More Info)
  5. Enhancing Surgical Mask Filtration Using Rubber Bands
  6. Making Your Own Reusable Elastomeric Respirator For Use During COVID-19
  7. Resources for Obtaining PPE:  ProjectN95,  #GetUsPPE,  Mask Match
  8. More PPE Resources, Info, and Research

Governmental Resources and Guidance

  1. CDC COVID-19 Info for Healthcare Professionals
  2. ECDC COVID-19 Updates
  3. WHO COVID-19 Daily Situation Reports
    1. WHO Biosafety Guidance for Handling COVID-19
  4. FDA COVID-19 Emergency Use Authorizations

Radiology Imaging Databases

  1. Radiology Databases List

Other Clinical Info

  1. General
    1. NEJM Video: How to Obtain a Nasopharyngeal Swab Specimen (Diagram)
    2. MGH Ground Rounds: Pathogenesis and Management of Respiratory Failure in COVID-19
    3. Nutrition Therapy in the Patient with COVID-19 Disease Requiring ICU Care
  2. Primary Care
    1. NEJM: Mild or Moderate COVID-19 (Diagram)
    2. BMJ: Management of Post-Acute COVID-19 in Primary Care
    3. JAMA: Proposed Framework and Timeline of the Spectrum of Post-Acute SARS-CoV-2 Disease
  3. Cardiovascular Involvement
  4. Pediatrics
    1. A Clinical Pathway for Hospitalized Pediatric Patients with Initial SARS-CoV-2 Infection (Tx Algorithm)
    2. Multisystem Inflammatory Syndrome in Children (MIS-C)
  5. Nursing Homes/Long-term Care
    1. CDC: Preparing for COVID-19 at Long-term Care Facilities and Nursing Homes
    2. CMS: COVID-19 Guidance for Nursing Homes
  6. Neurology
    1. BMC COVID-19 Neurology Protocols
  7. Other
    1. RCEM COVID-19 Tips and Resources
    2. Coronavirus Tech Handbook for Doctors
    3. Frontline COVID Guide
  8. Vaccine Info


  1. EPIC Templates for COVID Documentation
    1. Adult Respiratory Care Order Templates
    2. Charting Tool Templates for Patient Care
  2. MDCalc: Core COVID-19 Calculators
  3. COVID-19 Prognostic Models and Calculators
  4. CARDMEDIC: Communication Flashcards
  5. NEJM: COVID-19 Treatment Simulations
  6. COVID-19 Simulations
  7. COVID-19 Ventilator Simulator
  8. NEJM: Severe COVID-19 Clinical Vignette
  9. 360° Video: Best Practices for Resuscitation of COVID-19 Respiratory Failure
  10. COVID Ready Communication Playbook
  11. Communicating with Patient’s Families: Key Phrases

Last Updated on February 12, 2021